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Association between mesothelioma and non-occupational asbestos exposure: systematic review and meta-analysis

January 9, 2019 By Thomas Lamb

Background:  The risk of mesothelioma has been shown to be associated with exposure to asbestos fibers. Most of the existing literature focuses on occupational exposure; however, non-occupational asbestos exposure has also been identified as an important risk factor.

Objective:  To estimate the association between mesothelioma and non-occupational asbestos exposure, and evaluate control recruitment and exposure measurement methods.

Methods:  A systematic literature review was conducted to identify case-control (CC) and cohort studies that examined the association between mesothelioma and non-occupational exposure to asbestos, including neighborhood, domestic, and household exposure….

Conclusions:  Non-occupational asbestos exposure is significantly associated with an elevated risk of mesothelioma. Funnel plots indicated a potential of publication bias. Some [summary relative risk estimates (SRREs)]  should be interpreted with cautions because of high between-studies heterogeneity.

[Read article in full at original source]


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