Primary malignant mesothelioma (MPM) is a rare malignancy that arises from the epithelial cells that line visceral cavities. The primary pleural presentation is known as the most commonly seen presentation and is best recognized clinically. Less commonly, mesothelioma can arise from epithelial cells … More
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Recent News & Reports
Chrysotile asbestos—the deadly consequences of a retreat from national bans
Many in the global clinical and research community reacted with horror to the June 18, 2025, news that the Trump administration was requesting that the US Environmental Protection Agency (US EPA) should “reconsider” the country's ban on chrysotile asbestos. This ban had been previously enacted under … More
Optimizing the Pathological Diagnosis of Diffuse Malignant Peritoneal Mesothelioma
Background: Diffuse malignant peritoneal mesothelioma (DMPM) is the most common histological type of peritoneal mesothelioma (PM). Accurate histology and Ki67 assessment are crucial for treatment and prognosis, yet intra-tumoral heterogeneity may hinder preoperative diagnostics. A standardized … More
Prognostic importance of the neutrophil-to-lymphocyte ratio in malignant peritoneal mesothelioma patients receiving cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
Background: Malignant peritoneal mesothelioma (MPM) is a rare but aggressive cancer. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) was the preferred choice for selected patients. The purpose of this study was to thoroughly examine the impact of the combined … More
Long Road to Identifying Peritoneal Mesothelioma: An Elusive Diagnosis
Peritoneal mesothelioma is a rare and aggressive malignancy that often presents with non-specific abdominal symptoms such as ascites, leading to delayed diagnosis and treatment. It poses significant diagnostic challenges, especially in the absence of classical risk factors like asbestos … More
PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma
Lung-sparing radical pleurectomy with intraoperative photodynamic therapy (PDT) demonstrates remarkable survival for patients with pleural mesothelioma. Nevertheless, most patients treated with this multimodal approach will develop local tumor recurrence. An understanding of potential causes of … More