Law Offices of Thomas J. Lamb

  • Free Case Evaluation
  • Mesothelioma & Asbestos Diseases
  • Legal Compensation
  • Asbestos Overview
  • Common Questions
  • About Our Firm

Preoperative immunotherapy for mesothelioma shows favorable outcomes

December 15, 2022 By Thomas Lamb

In a study published recently in the journal Clinical Cancer Research, researchers at Baylor College of Medicine found that treating patients who have resectable malignant pleural mesothelioma, meaning that their tumor can be removed with surgery, with immunotherapy ahead of surgery resulted in favorable clinical outcomes. The study lays the groundwork for neoadjuvant immunotherapy in mesothelioma.

[This Clinical Cancer Research medical study report is “A Phase II Window of Opportunity Study of Neoadjuvant PD-L1 versus PD-L1 plus CTLA-4 Blockade for Patients with Malignant Pleural Mesothelioma“.]

“Mesothelioma is a devastating disease with low survivability,” said Dr. Bryan Burt, professor and chief of the David J. Sugarbaker Division of Thoracic Surgery in the Michael E. DeBakey Department of Surgery at Baylor and senior author of the paper. “Traditionally, this disease has defeated all standard therapies.”

Immune checkpoint inhibitors are drugs that activate the immune system to fight cancer. They have revolutionized the treatment of cancer in general, but only recently have been recognized to have some efficacy in mesothelioma. Recent research on the efficacy of immunotherapy for patients with unresectable mesothelioma showed favorable outcomes, which led Burt and colleagues to study this approach in patients with resectable mesothelioma.

“Surgery itself may not be curative, however combining surgery with some other modality of therapy often provides benefit,” said Burt, who also is a member of the Dan L Duncan Comprehensive Cancer Center at Baylor. “Our trial is an important step to evaluate whether checkpoint inhibitors are safe and feasible to give before surgery.”

One reason to give a therapy that increases the immune reactivity to a tumor pre-operatively is that the immunotherapy can activate an immune response that will persist after the tumor is resected. If the tumor tries to recur, the body has an existing memory immune response to fight it.

[Article continues at original source]


 Asbestos & Mesothelioma Information

  Asbestos-Mesothelioma Case Evaluation
Free.  Confidential.  No Obligation.

Filed Under: Mesothelioma Tagged With: Immune checkpoint inhibitor (ICI), Immunotherapy, malignant pleural mesothelioma (MPM), mesothelioma treatments

Do I Have A Possible Case?

If you have a possible asbestos disease or mesothelioma lawsuit, you can get a free, confidential, and no obligation case review from asbestos lawyer Tom Lamb.

Main Navigation Menu

  • Asbestos Information Overview
  • NC Asbestos Exposure Sites
  • Asbestos Cancers / Diseases
  • Legal Compensation
  • Free Case Evaluation
  • About Our Law Firm
  • Attorney Tom Lamb
  • Recent News & Reports
  • Frequently Asked Questions
  • Sitemap

Attorney Tom Lamb

TJL@LambLawOffice.com

Phone: 800-426-9535

Lumina Station, Suite 225
1908 Eastwood Road
Wilmington, North Carolina

Please know that you can use our Quick Contact Form to tell us about your case.

Lamb Law Office Newsletter

Lamb Law Office Newsletter provides periodic updates about some of the cases that we are working on for clients, as well as an information resource you might find helpful.

Subscribe using Form below.

Subscription Form

* indicates required

Our Other Website

LambLawOffice.com

Contact Information

Law Offices of Thomas J. Lamb, P.A.
1908 Eastwood Road, Suite 225
Wilmington, North Carolina 28403
910-256-2971 | 800-426-9535
TJL@LambLawOffice.com

  • Home
  • Disclaimer and Copyright Notices
  • Sitemap

Copyright © 2025 · Law Offices of Thomas J. Lamb, P.A.