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Clinical-pathological characteristics and prognostic factors for malignant peritoneal mesothelioma in the elderly

June 22, 2022 By Thomas Lamb

Background:  Malignant peritoneal mesothelioma (MPM) is a rare disease characterized by atypical symptoms, difficult diagnosis, variable course and poor prognosis, and it develops mainly in elderly individuals. The authors aimed to identify the clinical-pathological characteristics, prognosis, and prognostic factors in elderly [ malignant … [Read more...]

Filed Under: Medicine, Mesothelioma Tagged With: mesothelioma, peritoneal malignant mesothelioma, peritoneal mesothelioma

Biphasic Peritoneal Mesothelioma: A Lethal Clinical Entity

February 28, 2022 By Thomas Lamb

Abstract:  Mesotheliomas are a rare malignancy of the serosal membrane. Mainly it affects the pleural surfaces followed by the second most common location, “peritoneum.” The disease follows an aggressive pattern of spread, and by the time the diagnosis is established, the condition significantly spreads to distant locations. Diagnosis of malignant … [Read more...]

Filed Under: Medicine, Mesothelioma Tagged With: biphasic peritoneal mesothelioma, mesothelioma, peritoneal malignant mesothelioma, peritoneal mesothelioma

Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial

November 3, 2021 By Thomas Lamb

Background:  No phase 3 trial has yet shown improved survival for patients with pleural or peritoneal malignant mesothelioma who have progressed following platinum-based chemotherapy. The aim of this study was to assess the efficacy and safety of nivolumab, an anti-PD-1 antibody, in these patients. Methods:  This was a multicentre, … [Read more...]

Filed Under: Medicine, Mesothelioma Tagged With: malignant mesothelioma, malignant pleural mesothelioma (MPM), mesothelioma, mesothelioma treatments, Nivolumab, peritoneal malignant mesothelioma

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